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Articles (102)
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Oral delivery of nanoparticle-based vaccines

Marasini, Nirmal, Skwarczynski, Mariusz, Toth, Istvan

Journal:

Expert Review of Vaccines

Année:

2014

Langue:

english

Fichier:

PDF, 749 KB

english, 2014

Recent advances in peptide-based subunit nanovaccines

Skwarczynski, Mariusz, Toth, Istvan

Journal:

Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 3.81 MB

english, 2014

Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite

Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

Journal:

ChemMedChem

Année:

2015

Langue:

english

Fichier:

PDF, 1007 KB

english, 2015

Back Cover: Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite (ChemMedChem 10/2015)

Fuaad, Abdullah A. H. Ahmad, Pearson, Mark S., Pickering, Darren A., Becker, Luke, Zhao, Guangzu, Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

Journal:

ChemMedChem

Année:

2015

Fichier:

PDF, 3.34 MB

2015

Inulin: A New Adjuvant With Unknown Mode of Action

Skwarczynski, Mariusz

Journal:

EBioMedicine

Année:

2017

Langue:

english

Fichier:

PDF, 172 KB

english, 2017

Peptide-Based Subunit Nanovaccines

Skwarczynski, Mariusz, Toth, Istvan

Journal:

Current Drug Delivery

Année:

2011

Langue:

english

Fichier:

PDF, 275 KB

english, 2011

Enantioselective hydrolysis of 1-butyryloxyalkylphosphonates by lipolytic microorganisms: Pseudomonas fluorescens and Penicillium citrinum

Mariusz Skwarczyński, Barbara Lejczak, Paweł Kafarski

Journal:

Chirality

Année:

1999

Langue:

english

Fichier:

PDF, 114 KB

english, 1999

Polyacrylate Dendrimer Nanoparticles: A Self-Adjuvanting Vaccine Delivery System

Mariusz Skwarczynski, Mehfuz Zaman, Carl N. Urbani, I-Chun Lin, Zhongfan Jia, Michael R. Batzloff, Michael F. Good, Michael J. Monteiro, Istvan Toth

Journal:

Angewandte Chemie

Année:

2010

Langue:

english

Fichier:

PDF, 485 KB

english, 2010

Polyacrylate Dendrimer Nanoparticles: A Self-Adjuvanting Vaccine Delivery System

Mariusz Skwarczynski, Mehfuz Zaman, Carl N. Urbani, I-Chun Lin, Zhongfan Jia, Michael R. Batzloff, Michael F. Good, Michael J. Monteiro, Istvan Toth

Journal:

Angewandte Chemie International Edition

Année:

2010

Langue:

english

Fichier:

PDF, 504 KB

english, 2010

ON intramolecular acyl migration reaction in the development of prodrugs and the synthesis of difficult sequence-containing bioactive peptides

Youhei Sohma, Yoshio Hayashi, Mariusz Skwarczynski, Yoshio Hamada, Masato Sasaki, Tooru Kimura, Yoshiaki Kiso

Journal:

Biopolymers

Année:

2004

Langue:

english

Fichier:

PDF, 548 KB

english, 2004

Controlled Production of Amyloid β Peptide from a Photo-Triggered, Water-Soluble Precursor “Click Peptide“

Atsuhiko Taniguchi, Mariusz Skwarczynski, Youhei Sohma, Takuma Okada, Keisuke Ikeda, Halan Prakash, Hidehito Mukai, Yoshio Hayashi , Tooru Kimura, Shun Hirota, Katsumi Matsuzaki, Yoshiaki Kiso

Journal:

ChemBioChem

Année:

2008

Langue:

english

Fichier:

PDF, 660 KB

english, 2008

ChemInform Abstract: Mercuric Triflate—TMU Catalyzed Hydration of Terminal Alkyne to Give Methyl Ketone under Mild Conditions.

Mugio Nishizawa, Mariusz Skwarczynski, Hiroshi Imagawa, Takamichi Sugihara

Journal:

ChemInform

Année:

2002

Fichier:

PDF, 30 KB

2002

Mercuric Triflate Catalyzed Hydroxylative Carbocyclization of 1,6-Enynes.

Mugio Nishizawa, Veejendra K. Yadav, Mariusz Skwarczynski, Hiroko Takao, Hiroshi Imagawa, Takumichi Sugihara

Journal:

ChemInform

Année:

2003

Fichier:

PDF, 168 KB

2003

O—N Intramolecular Acyl Migration Strategy in Water-Soluble Prodrugs of Taxoids.

Mariusz Skwarczynski, Youhei Sohma, Maiko Kimura, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

ChemInform

Année:

2004

Fichier:

PDF, 123 KB

2004

ChemInform Abstract: Lipid Core Peptide System for Gene, Drug, and Vaccine Delivery

Wei Zhong, Mariusz Skwarczynski, Istvan Toth

Journal:

ChemInform

Année:

2010

Fichier:

PDF, 15 KB

2010

Experimental evaluation of three heating systems commonly used in the residential sector

Tomasz Cholewa, Alicja Siuta-Olcha, Mariusz A. Skwarczyński

Journal:

Energy and Buildings

Année:

2011

Langue:

english

Fichier:

PDF, 758 KB

english, 2011

Development of novel water-soluble photocleavable protective group and its application for design of photoresponsive paclitaxel prodrugs

Mayo Noguchi, Mariusz Skwarczynski, Halan Prakash, Shun Hirota, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 465 KB

english, 2008

Development of first photoresponsive prodrug of paclitaxel

Mariusz Skwarczynski, Mayo Noguchi, Shun Hirota, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 308 KB

english, 2006

Self-adjuvanting polyacrylic nanoparticulate delivery system for group A streptococcus (GAS) vaccine

Mehfuz Zaman, Mariusz Skwarczynski, Jessica M. Malcolm, Carl N. Urbani, Zhongfan Jia, Michael R. Batzloff, Michael F. Good, Michael J. Monteiro, Istvan Toth

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 308 KB

english, 2011

Development of highly pure α-helical lipoglycopeptides as self-adjuvanting vaccines

Wei Zhong, Mariusz Skwarczynski, Pavla Simerska, Michael F. Good, Istvan Toth

Journal:

Tetrahedron

Année:

2009

Langue:

english

Fichier:

PDF, 349 KB

english, 2009

‘O-Acyl isopeptide method’ for the efficient synthesis of difficult sequence-containing peptides: use of ‘O-acyl isodipeptide unit’

Youhei Sohma, Atsuhiko Taniguchi, Mariusz Skwarczynski, Taku Yoshiya, Fukue Fukao, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Année:

2006

Langue:

english

Fichier:

PDF, 165 KB

english, 2006

‘Click peptide’: a novel ‘O-acyl isopeptide method’ for peptide synthesis and chemical biology-oriented synthesis of amyloid β peptide analogues

Youhei Sohma, Atsuhiko Taniguchi, Taku Yoshiya, Yousuke Chiyomori, Fukue Fukao, Setsuko Nakamura, Mariusz Skwarczynski, Takuma Okada, Keisuke Ikeda, Yoshio Hayashi, Tooru Kimura, Shun Hirota, Katsumi

Journal:

Journal of Peptide Science

Année:

2006

Langue:

english

Fichier:

PDF, 237 KB

english, 2006

Accurate assay of enantiopurity of 1-hydroxy- and 2-hydroxyalkylphosphonate esters

Ewa Żymańczyk-Duda, Mariusz Skwarczyński, Barbara Lejczak, Pawel Kafarski

Journal:

Tetrahedron: Asymmetry

Année:

1996

Langue:

english

Fichier:

PDF, 204 KB

english, 1996

O–N Intramolecular acyl migration strategy in water-soluble prodrugs of taxoids

Mariusz Skwarczynski, Youhei Sohma, Maiko Kimura, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2003

Langue:

english

Fichier:

PDF, 167 KB

english, 2003

Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery

Zyta M. Ziora, Norbert Wimmer, Roger New, Mariusz Skwarczynski, Istvan Toth

Journal:

Carbohydrate Research

Année:

2011

Langue:

english

Fichier:

PDF, 465 KB

english, 2011

ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids

Zyta Ziora, Mariusz Skwarczynski, Yoshiaki Kiso

Journal:

ChemInform

Année:

2012

Fichier:

PDF, 19 KB

2012

O−N Intramolecular Alkoxycarbonyl Migration of Typical Protective Groups in Hydroxyamino Acids

Skwarczynski, Mariusz, Sohma, Youhei, Noguchi, Mayo, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki

Journal:

Journal of Organic Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 61 KB

english, 2006

?O-Acyl isopeptide method? for peptide synthesis: synthesis of forty kinds of ?O-acyl isodipeptide unit? Boc-Ser/Thr(Fmoc-Xaa)-OH

Yoshiya, Taku, Taniguchi, Atsuhiko, Sohma, Youhei, Fukao, Fukue, Nakamura, Setsuko, Abe, Naoko, Ito, Nui, Skwarczynski, Mariusz, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki

Journal:

Organic & Biomolecular Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 271 KB

english, 2007

Microwave-assisted synthesis of difficult sequence-containing peptides using the isopeptide method

Hussein, Waleed M., Liu, Tzu-Yu, Toth, Istvan, Skwarczynski, Mariusz

Journal:

Organic & Biomolecular Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 419 KB

english, 2013

Liposome-based delivery system for vaccine candidates: constructing an effective formulation

Giddam, Ashwini Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz, Toth, Istvan

Journal:

Nanomedicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2012

Self-Adjuvanting Polymer–Peptide Conjugates As Therapeutic Vaccine Candidates against Cervical Cancer

Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan, Skwarczynski, Mariusz

Journal:

Biomacromolecules

Année:

2013

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2013

No Auxiliary, No Byproduct Strategy for Water-Soluble Prodrugs of Taxoids: Scope and Limitation of O−N Intramolecular Acyl and Acyloxy Migration Reactions †

Skwarczynski, Mariusz, Sohma, Youhei, Noguchi, Mayo, Kimura, Maiko, Hayashi, Yoshio, Hamada, Yoshio, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 240 KB

english, 2005

Paclitaxel Prodrugs: Toward Smarter Delivery of Anticancer Agents

Skwarczynski, Mariusz, Hayashi, Yoshio, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 588 KB

english, 2006

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah AH, Jia, Zhongfan, Zaman, Mehfuz, Hartas, Jon, Ziora, Zyta M, Lin, I-Chun, Moyle, Peter M, Batzloff, Michael R, Good, Michael F, Monteiro, Michael J, Skwarczynski, Mariusz, Toth,

Journal:

Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2014

Design and Synthesis of Lipopeptide–Carbohydrate Assembled Multivalent Vaccine Candidates Using Native Chemical Ligation

Zhong, Wei, Skwarczynski, Mariusz, Fujita, Yoshio, Simerska, Pavla, Good, Michael F., Toth, Istvan

Journal:

Australian Journal of Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 331 KB

english, 2009

Mercuric Triflate Catalyzed Hydroxylative Carbocyclization of 1,6-Enynes

Nishizawa, Mugio, Yadav, Veejendra K., Skwarczynski, Mariusz, Takao, Hiroko, Imagawa, Hiroshi, Sugihara, Takumichi

Journal:

Organic Letters

Année:

2003

Langue:

english

Fichier:

PDF, 60 KB

english, 2003

A Novel Approach of Water-Soluble Paclitaxel Prodrug with No Auxiliary and No Byproduct: Design and Synthesis of Isotaxel

Hayashi, Yoshio, Skwarczynski, Mariusz, Hamada, Yoshio, Sohma, Youhei, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 54 KB

english, 2003

Thymine, adenine and lipoamino acid based gene delivery systems

Skwarczynski, Mariusz, Ziora, Zyta M., Coles, Daniel J., Lin, I-Chun, Toth, Istvan

Journal:

Chemical Communications

Année:

2010

Langue:

english

Fichier:

PDF, 982 KB

english, 2010

Self-adjuvanting vaccine against group A streptococcus: Application of fibrillized peptide and immunostimulatory lipid as adjuvant

Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz, Toth, Istvan

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2014

Toll-like receptor agonists: a patent review (2011 – 2013)

Hussein, Waleed M, Liu, Tzu-Yu, Skwarczynski, Mariusz, Toth, Istvan

Journal:

Expert Opinion on Therapeutic Patents

Année:

2014

Langue:

english

Fichier:

PDF, 715 KB

english, 2014

The immune system likes nanotechnology

Toth, Istvan, Skwarczynski, Mariusz

Journal:

Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2014

Alkylation of Potassium 1-(N-Benzyloxycarbonylamino)alkylphosphonates and Phosphinates in the Presence of 18-Crown-6

Skwarczyński, Mariusz, Kafarski, Pawel

Journal:

Synthetic Communications

Année:

1995

Langue:

english

Fichier:

PDF, 220 KB

english, 1995

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K, Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M, Batzloff, Michael R, Good, Michael F, Toth, Istvan

Journal:

Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 3.42 MB

english, 2014

Handbook of Biologically Active Peptides || Lipo-Peptides/Saccharides for Peptide Vaccine Delivery

Skwarczynski, Mariusz

Année:

2013

Langue:

english

Fichier:

PDF, 662 KB

english, 2013

The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni

Ahmad Fuaad, Abdullah A.H., Roubille, Romain, Pearson, Mark S., Pickering, Darren A., Loukas, Alex C., Skwarczynski, Mariusz, Toth, Istvan

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 937 KB

english, 2015

Recent progress in adjuvant discovery for peptide-based subunit vaccines

Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Skwarczynski, Mariusz, Toth, Istvan

Journal:

Human Vaccines & Immunotherapeutics

Année:

2014

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2014

The Use of Lypolitic Microorganisms Pseudomonas fluorescens and Penicillium citrinum for the Preparation of Optically Active 1 -Hydroxyalkylphosphonates

Lejczak, Barbara, Haliniarz, Ewa, Skwarczynski, Mariusz, Kafarski, Pawel

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Année:

1996

Langue:

english

Fichier:

PDF, 68 KB

english, 1996

A study on the encapsulation of an occludin lipophilic derivative in liposomal carriers

Cupri, Sarha, Graziano, Adriana C. E., Cardile, Venera, Skwarczynski, Mariusz, Toth, Istvan, Pignatello, Rosario

Journal:

Journal of Liposome Research

Année:

2015

Langue:

english

Fichier:

PDF, 393 KB

english, 2015

Application of the O-N Intramolecular Acyl Migration Reaction in Medicinal Chemistry

Skwarczynski, Mariusz, Kiso, Yoshiaki

Journal:

Current Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 285 KB

english, 2007

Advances in Peptide-based Human Papillomavirus Therapeutic Vaccines

Liu, Tzu-Yu, M. Hussein, Waleed, Toth, Istvan, Skwarczynski, Mariusz

Journal:

Current Topics in Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 199 KB

english, 2012